Carlos R. – Amputation Due to Oxbryta-Induced Leg Ulcers

Settlement Amount: $1.9 Million
Injury Type: Below-Knee Amputation from Non-Healing Wounds

Background

Carlos R., a 40-year-old construction worker from Phoenix, developed severe leg ulcers 6 months after starting Oxbryta. Despite wound care, infection led to guillotine amputation of his right leg.

Medical Devastation

  • Amputation Aftermath:
    • 3 revision surgeries due to persistent osteomyelitis
    • Phantom limb pain requiring spinal cord stimulator
  • Financial Ruin:
    • Lost union health benefits after disability discharge
    • Home foreclosure during recovery

Defense Tactics

  1. Blamed “poor diabetic control” (Carlos is non-diabetic)
  2. Argued ulcers were pre-existing
  3. Delayed discovery requests for 14 months

Injurease’s Action

  • Commissioned vascular study proving Oxbryta impaired microcirculation
  • Found 22 similar ulcer cases in FDA FAERS database
  • Negotiated interim funding for prosthetic fitting

Legal Triumphs

  • Proved Pfizer:
    1. Knew about ulcer risks from GBT440-042 trial
    2. Marketed to manual laborers despite contraindications
    3. Destroyed post-market surveillance data

Settlement Details

  • $1.9M covering:
    • $650K future prosthetics/accessibility retrofits
    • $300K lost pension benefits
    • $950K pain/suffering
  • Vocational rehab partnership with UA Local 469

Carlos Today:
“I built skyscrapers for 20 years. Now I can’t climb a ladder. Injurease made sure Pfizer paid for what they took from me.”

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